Resource Library

Long-Term Potentiation and Closed-Loop Learning in Paired Brain Organoids for CNS Drug Discovery

Preclinical Neurotoxicity Predictions using a High-Throughput Brain Organoid Model

The Future of Organoid Intelligence

Human Peripheral Nerve-on-a-Chip on a Multiwell Microelectrode Array as a Scalable Preclinical Neurotoxicity Assay

CNS-3D Organoids 96-Well Plate

CNS-3D Organoids 384-Well Plate

CNS-3D Organoids FLIPR Assay

CNS-3D Organoids

PNS-3D Organoid Services

Chemotherapy-Induced Peripheral Neuropathy Assessment in PNS-3D Technology

Disease Modeling in CNS-3D Technology for High-Throughput Efficacy Assessment of Rescue Therapeutics

Modeling CDKL5 Deficiency Disorder with CNS-3D Organoids for Streamlined Target Discovery

Improving the Stability and Reproducibility of Clinical Neurotoxicity Predictions from a High-throughput Compatible Neural Organoid Platform

Comparison of a 3D Nerve-on-a-Chip Peripheral Nerve Model to 2D Neuronal Assays for Clinical Translation with Antibody Drug Conjugate (ADC) Toxicity Screening

Predicting Clinical Neurotoxicity Using Functional Organoids

Translating Neurological Stem Cell Research into Therapies for Today's Patients

Onset of CIPN Delayed Through SARM1 Inhibition in Human NerveSim Preclinical Drug Discovery Platform

Clinically Related Rare Neurodevelopmental Disorders Display Distinct Functional Phenotypes in Human iPSC-derived Cortical Organoids

Identification of a Potential Therapeutic Compound for Rett Syndrome Using a Highly Homogenous Human iPSC-derived Cortical Organoid Screening Platform

High-throughput Functional and Morphological Neurotoxicity Screening in Human NerveSim

Comparative Assessment of Ca²⁺ Oscillations in 2- and 3-Dimensional hiPSC-Derived and Isolated Cortical Neuronal Networks

Assessment of a 3D Neural Spheroid Model to Detect Pharmaceutical-Induced Neurotoxicity

A Multiparametric Calcium Signal Screening Platform Using iPSC-Derived Cortical Neural Spheroids

Screening for Modulators of Neural Network Activity in 3D Human iPSC-Derived Cortical Spheroids

Modeling Chemotherapy-induced Peripheral Neuropathy using a Nerve-on-a-Chip Microphysiological System

Functional and Mechanistic Neurotoxicity Profiling Using Human iPSC-Derived Neural 3D Cultures

Neurological Drug Discovery and Toxicology Screening

Human Schwann Cells: Importance for Peripheral Neuropathy Preclinical Research

Human Dorsal Root Ganglia Studies on Ectopic Spontaneous Activity

Functional Organoids and their Applications for Disease Modeling

ADCs and Peripheral Neuropathy: The Need for New, Predictive Assays

Accelerating Care & Research for Neurological Diseases

A Case Study on Chemotherapeutic Drug-induced Peripheral Neuropathy

Novel Neurotoxicity Screening Platform to Examine Functional Changes in Rodent Dorsal Root Ganglia and Human iPSC-derived Sensory Neuron Cultures

Nerve-On-A-Chip for Modelling Motor Neuron Diseases and Preclinical Neurotoxicity Testing

Glial Cell Type Composition in a 3D Model of the Central Nervous System

Evaluating Human Nerve Conduction Velocity In Vitro as a Novel Metric for Assessing Chemotherapeutics-induced Peripheral Neuropathy

Development of Rat DRG Model for Predicting Peripheral Neuroinflammation and Neurotoxicity of Therapeutic Agents

Development of an In Vitro Human-derived 3D Model of Dorsal Horn Pain Signaling

Development of a High-Content Human Co-culture Model to Investigate Chemotherapy-Induced Peripheral Neuropathy

Assessing Chemotherapeutics Neurotoxicity Using Human Cells Based High-Throughput Neuronal-Schwann Cells Culture System

An Engineered 3D Peripheral Human "Nerve-on-a-Chip": A Novel Assessment for Neurotoxicity In Vitro

A Robust, High-throughput Electrophysiology Platform for Drug Screening in a Peripheral Nerve-on-a-Chip Microphysiological System

A Novel, High-throughput Electrophysiology Platform for Compound Screening with a Peripheral Nerve Microphysiological System

A Nondestructive, Image-based Cytotoxicity Assessment for Combined Safety and Efficacy Screening in Human-iPSC Derived Organoids

A Model for High-throughput Therapeutic Screening of Peripheral Neuropathy in a Human 3D Nerve-on-a-Chip Microphysiological System

A High-throughput Electrophysiology Platform for Compound screening with a Peripheral Nerve Microphysiological System

A 3D Human Model for Preclinical Drug Screening using a Myelinated Nerve-on-a-Chip Micro-physiological System

3D Nerve-on-a-Chip Model Effectively Screens Neurotoxic Compounds

Application of a Dual Human Cell System to Measure Potential Off-target Induced Peripheral Neuropathy (PN) for Antibody Drug Conjugate (ADC) candidates and Other Developing Chemotherapeutics

Microengineered Peripheral Nerve-on-a-chip for Preclinical Physiological Testing

A Human Brain Microphysiological System Derived from Induced Pluripotent Stem Cells to Study Neurological Diseases and Toxicity

Rotenone Exerts Developmental Neurotoxicity in a Human Brain Spheroid Model

Engineering a 3D functional human peripheral nerve in vitro using the Nerve-on-a-Chip platform

Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model

Altered Network and Rescue of Human Neurons Derived from Individuals with Early-Onset Genetic Epilepsy

Advances in 3D Neuronal Microphysiological Systems: Towards a Functional Nervous System on a Chip

Modeling Chemotherapy-Induced Peripheral Neuropathy Using a Nerve-on-a-Chip Microphysiological System

Fabrication and Characterization of 3D Printed, 3D Microelectrode Arrays for Interfacing with a Peripheral Nerve-on-a-Chip